Who is at risk for thrombocytopenia?Asked by: Minerva Nitzsche
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People who are at highest risk for thrombocytopenia are those affected by one of the conditions or factors discussed in "What Causes Thrombocytopenia?" This includes people who: Have certain types of cancer, aplastic anemia, or autoimmune diseases. Are exposed to certain toxic chemicals.View full answer
Also, Who is most likely to get thrombocytopenia?
Who does ITP affect? ITP is more common among children than adults, most often occurring around two to four years of age. Estimates suggest that ITP affects one in every 10,000 children. Among adults, young women are more likely to develop ITP than any other group, for reasons unknown.
One may also ask, What are 3 causes of thrombocytopenia?.
- Alcohol use disorder and alcoholism.
- Autoimmune disease which causes ITP. ...
- Bone marrow diseases, including aplastic anemia, leukemia, certain lymphomas and myelodysplastic syndromes.
- Cancer treatments like chemotherapy and radiation therapy.
In respect to this, What are the risks of thrombocytopenia?
- Adverse effects of treatment.
- Excessive or uncontrollable bleeding.
- Gastrointestinal bleeding.
- Intracerebral hemorrhage (bleeding in the brain)
- Severe nosebleeds.
Who can get thrombocytopenia?
Platelets stop bleeding by clumping and forming plugs in blood vessel injuries. Thrombocytopenia might occur as a result of a bone marrow disorder such as leukemia or an immune system problem. Or it can be a side effect of taking certain medications. It affects both children and adults.
Other medicines that cause drug-induced thrombocytopenia include:
- Gold, used to treat arthritis.
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
ITP does not turn into a more serious blood disorder, like leukemia or aplastic anemia. It is usually not a sign that their child will later develop other autoimmune conditions, such as systemic lupus erythematosus (SLE or “lupus”).
The variety of symptoms in ITP is affected by your platelet count. The lower your platelet count is, the more likely you are to have spontaneous and unexpected bleeding, both internally and externally. Without treatment to correct platelet counts, bleeding can become severe and life-threatening.
Low Platelets Thrombocytopenia
Take special precautions with personal hygiene. Avoid falls in the shower or tub by using slip guard mats. Keep your teeth clean with a soft toothbrush. Do not use alcohol-based mouthwashes. Do not use dental floss.
A normal platelet count ranges from 150,000 to 450,000 platelets per microliter of blood. Having more than 450,000 platelets is a condition called thrombocytosis; having less than 150,000 is known as thrombocytopenia. You get your platelet number from a routine blood test called a complete blood count (CBC).
Age-associated decrease in Platelet Count
Platelet count is inversely associated with age.
Drs. Everson and Toth, together with Anne Folley present exciting results indicating that sleep deprivation in rats arrests new bone formation, decreases fat within the red marrow and increases platelet levels.
Platelet count Platelets help stop bleeding by sticking together to form blood clots, which “plug” cuts. A normal platelet count range is 140 to 400 K/uL. Sometimes, your CBC may show that your counts or values are too low.
Immune thrombocytopenia usually happens when your immune system mistakenly attacks and destroys platelets, which are cell fragments that help blood clot. In adults, this may be triggered by infection with HIV , hepatitis or H. pylori — the type of bacteria that causes stomach ulcers.
How is ITP treated? Some adults with mild ITP may not need any treatment, but will be monitored with occasional blood tests. There is no cure for ITP and treatment is used to raise the platelet count to counteract symptoms.
ITP (immune thrombocytopenic purpura) is generally considered a benign disease. Despite what may be severe thrombocytopenia, most patients with ITP do not suffer significant bleeding episodes. Mortality is rare, and the majority of cases are managed successfully with conventional treatments.
Not everyone with a low platelet count needs treatment. Some conditions that cause a low platelet count will eventually clear up. The platelet count will return to healthy levels in those cases. However, people with severe cases may need treatment.
- Eating more leafy greens. ...
- Eating more fatty fish. ...
- Increasing folate consumption. ...
- Avoiding alcohol. ...
- Eating more citrus. ...
- Consuming more iron-rich foods. ...
- Trying a chlorophyll supplement. ...
- Avoiding vitamin E and fish oil supplements.
One 2008 study found that coffee's phenolic acids create anti-platelet effects. While phenolic acid doesn't necessarily affect the number of platelets you have, it can significantly reduce their function. So if you're fighting low platelet counts, such studies suggest that drinking coffee can make matters worse.
Key points about immune thrombocytopenic purpura
ITP is a blood disorder. With this disease, you have a lower amount of platelets than normal in your blood. A decrease in platelets can result in easy bruising, bleeding gums, and internal bleeding. ITP may happen suddenly and go away in about 6 months.
In the majority of people with ITP, the condition isn't serious or life-threatening. Acute ITP in children often resolves within six months or less without treatment. Chronic ITP can last for many years. People can live for many decades with the disease, even those with severe cases.
When the platelet count drops below 20,000, the patient may have spontaneous bleeding that may result in death. Thrombocytopenia occurs due to platelet destruction or impaired platelet production.
Immune Thrombocytopenic Purpura (ITP) is in rare cases secondary to solid tumors, particularly breast cancer. In these cases, the clinical course of the ITP may follow the clinical course of the primary tumor, and remission of the ITP may be induced by treatment of the primary tumor.
The incidence of ITP increases with age and is more common over the age of 60. Among adults (age 30-60) diagnosed with chronic ITP, there are 2.6 cases among women for every case involving a male. In older adults, about the same number of men and women are diagnosed with ITP.
Certain cancers such as leukemia or lymphoma can lower your platelet count. The abnormal cells in these cancers can crowd out healthy cells in the bone marrow, where platelets are made. Less common causes of a low platelet count include: Cancer that spreads to the bone.